High-Dose Olanzapine for Bipolar Depression
نویسندگان
چکیده
منابع مشابه
Olanzapine/Fluoxetine Combination Affirmed for Bipolar Depression
Dr Marcus Silva, University of Brasilia, and colleagues relate in the April issue of Journal of Affective Disorders that their findings “support a therapeutic role for OFC as an alternative for bipolar depressed patients with indications for olanzapine use.” The investigators characterize their study, which included data on lamotrigine, as the only meta-analysis to address the efficacy of OFC i...
متن کاملEfficacy of olanzapine and olanzapine-fluoxetine combination in the treatment of bipolar I depression.
BACKGROUND Despite the longer duration of the depressive phase in bipolar disorder and the frequent clinical use of antidepressants combined with antipsychotics or mood stabilizers, relatively few controlled studies have examined treatment strategies for bipolar depression. OBJECTIVE To examine the use of olanzapine and olanzapine-fluoxetine combination in the treatment of bipolar I depressio...
متن کاملHigh-dose olanzapine orally disintegrating tablets for treatment-resistant psychosis.
Sir: Olanzapine is a thienobenzodiazepine antipsychotic that has a broad in vitro affinity for several receptors, including serotonergic, cholinergic, dopaminergic, and adrenergic receptors. Olanzapine is approved for treatment of psychoses at doses up to 20 mg/day. New research suggests benefits of higher doses of olanzapine. Anecdotal case reports highlight the benefits of olanzapine at 50 mg...
متن کاملUse of very-high-dose olanzapine in treatment-resistant schizophrenia.
Schizophrenia is a chronic illness with a progressive course that can be marked by resistance to antipsychotic treatment. This can make therapeutic support challenging for the practitioner, with results that are partial and unsatisfactory. In the literature, treatment with high-dose olanzapine (>20mg/day) appears to be a good alternative to clozapine, the gold standard for treatment-resistant s...
متن کاملQuality of life in children and adolescents with bipolar I depression treated with olanzapine/fluoxetine combination
BACKGROUND We examined the efficacy of olanzapine/fluoxetine combination (OFC) in improving health-related quality of life (QoL) in the treatment of bipolar depression in children and adolescents. METHODS Patients aged 10-17 years with bipolar I disorder, depressed episode, baseline children's depression rating scale-revised (CDRS-R) total score ≥40, Young Mania Rating Scale (YMRS) total scor...
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ژورنال
عنوان ژورنال: The Primary Care Companion For CNS Disorders
سال: 2014
ISSN: 2155-7780
DOI: 10.4088/pcc.13l01620